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Proteolytic antibodies are a novel therapeutic modality that has the potential to revolutionize antibody-based therapeutics. The overall goal of this project is to develop potent proteolytic human monoclonal antibodies mAb against a new target for treatment of psoriasis. Several recent studies demonstrate a key role for the keratinocyte growth factor amphiregulin AR in the pathogenesis of psoriasis. AR-neutralizing antibodies given at high doses alleviate some of the characteristic lesions in human psoriatic skin transplanted onto immunocompromised mice. However, grams of passively administered antibodies will be required for chronic therapy, a serious limitation of the traditional monoclonal antibody approach.
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Robert Balint, Actor: Branded. Robert Balint was born on June 25, in Hungary. He is an actor. View the profiles of people named Robert Balint. Join Facebook to connect with Robert Balint and others you may know. Facebook gives people the power to.
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